United States Route 422 and Pennsylvania Route 60 join for two miles near New Castle in Lawrence County.

Douglas Kerr 11/23/04
Westbound on Business US 422 at the northern split interchange of US 422/PA 60. The foreground overpass carries the lone flyover ramp in the cloverleaf interchange. The background overpass carries mainline US 422/PA 60. The New Castle bypass (US 422 and PA 60) was built back in the days of button-copy guide signs spelled-out route designations (e.g., "PA 60" instead of a keystone sign with a "60" in it).